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confirmed that research. Using positron emissiontomography (PET scan) and a special injection of a radioactive material, the researchers were able to get a visual sense of the density of the CB1 receptors in the brain.

The study compared 11 subjects diagnosed with cannabis dependence to 19 volunteers. The images showed that chronic cannabis consumers did, indeed, show lower receptor density. This is an important signifier of tolerance. They then performed these scans again, testing participants during a period of abstinence.

This where the results get interesting. According to the study,

[CB1 downregulation] begins to reverse surprisingly rapidly upon termination of cannabis use and may continue to increase over time.

Amazingly, cannabis tolerance begins to reverse within two days after abstaining from the herb. At the 28-day mark, tolerance continued to improve. This is valuable information for medical cannabis patients, asthis means dosage will change should they stop and start their treatment again.

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receptors start to spring back just a couple of days after abstaining, the density of CB1 receptors in cannabis consuming participants was still lower than the healthy controls at the four-week mark. Though, should participants continue to abstain, things are predicted to catch up to “normal”.

Many cannabis regulars take tolerance breaks to maintain efficacy with the herb. A tolerance break is a short period of abstinence from the herb. As this study suggests, a mere two days of abstinence seems to be enough to kickstart the upregulation process.

Medical cannabis patients should always work with a health care provider before making major changes to a treatment plan. However, casual cannabis consumers may have a few T-break tricks at their fingers.

Here are three tips for hacking cannabis tolerance:

Want to kick your tolerance without much disruption? Start consuming smaller and smaller amounts of cannabis. “Microdosing”, or consuming a very small amount of a substance on a continuous basis, is becoming more popular.

Cannabis tolerance happens when larger and larger amounts of the herb are needed to produce an effect. Switching back to small doses of the plant will not likely be as effective as abstaining. However, it’s a decent compromise for a complete break.

Both psychoactive THC and nonpsychoactive cannabidiol (CBD) engage the endocannabinoid system . However, these two compounds work in fundamentally different ways. For some, switching to CBD may provide a nice alternative for THC.

A “Blue Moon” is the name given to the second full moon in a calendar month. Since there are roughly 29.5 days between full moons, it is unusual for two full moons to occur in a 30 or 31 day month (and impossible to fit into a 28 or 29 day month, so February can never have a Blue Moon). The saying “Once in a Blue Moon” means a rare occurrence; on average there will be one Blue Moon every 2.5 years. Calico Racing has celebrated the Blue Moon in 2012, 2015, and will again in 2018.

Once in a DOUBLE Blue Moon: In 2018 we will celebrate something truly rare, a situation which only takes place about four times a century: two Blue Moons occurring in the same year. The last time this happened was in 1999, and after 2018 we won’t have a double blue moon again until 2037, 2067, and 2094! Sounds like a good excuse to party!

Once in a DOUBLE Blue Moon:

You can choose from the following start times, or DOUBLE DOWN and run both!

6:45pm DOUBLE DOWN You may deduct $5 from the combined entry fees if you are running any combination of DAY and NIGHT races. No code required- it is encoded into the online registration platform.When registering online, choose your morning and evening race distances, the $5 multi-event discount will be deducted in your cart.

*ALL raceentries include acustom technical shirt, finishers' medal, event timing, post race food, award eligibility, aid stations, and a fun time!

You may deduct $5 from the combined entry fees if you are running any combination of DAY and NIGHT races. No code required- it is encoded into the online registration platform. When registering online, choose your morning and evening race distances, the $5 multi-event discount will be deducted in your cart.

** Those running both AM and PM races will receive 1 shirt and 2 medals !

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Sunset Regional Park : History Walk Trails (Paved)

Sunset Regional Park : History Walk Trails (Paved)

2601 East Sunset Road, Las Vegas, NV 89120

SUNSET PARK MAP

The History Walk paved trails are completely removed from vehicular traffic. The path is mostly flat with only slight inclines/ declines- setting the stage for a PR, or perfect for the beginning runner. The course is walker and stroller friendly. Enjoy views of the Las Vegas Strip, Frenchman's Mountain, landing aircraft, and bunnies!

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